eif-3.E

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in nucleus. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in head and tail. Is an ortholog of human EIF3E (eukaryotic translation initiation factor 3 subunit E).

sdz-26

Caenorhabditis elegans

Expressed in E; Ea; and Ep.

sdz-23

Caenorhabditis elegans

Predicted to enable Notch binding activity. Predicted to be located in membrane. Expressed in E; Ea; and Ep.

clec-224

Caenorhabditis elegans

Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Is an ortholog of human CLEC4E (C-type lectin domain family 4 member E).

lin-62

Caenorhabditis elegans

end-3

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate specification and mesodermal cell fate specification. Located in nucleus. Expressed in E; E lineage cell; Ea; Ep; and intestine.

pges-2

Caenorhabditis elegans

Predicted to enable prostaglandin-E synthase activity. Predicted to be involved in prostaglandin biosynthetic process. Predicted to be located in mitochondrion. Expressed in hypodermis; intestinal cell; lumbar ganglion; muscle cell; and retrovesicular ganglion. Is an ortholog of human PTGES2 (prostaglandin E synthase 2).

sdz-1

Caenorhabditis elegans

Involved in mesendoderm development. Expressed in several structures, including E; Ea; Ep; MSpa; and somatic gonad precursor.

wee-1.1

Caenorhabditis elegans

Predicted to enable protein kinase activity. Predicted to be involved in meiotic cell cycle and negative regulation of G2/MI transition of meiotic cell cycle. Predicted to be located in cytoplasm and nucleus. Expressed in Ea and Ep. Is an ortholog of human PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1).

ges-1

Caenorhabditis elegans

Enables carboxylesterase activity. Involved in cellular catabolic process. Located in peroxisome. Expressed in pharynx. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1).