- Y6B3B.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable endonuclease activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be part of preribosome, large subunit precursor. Human ortholog(s) of this gene implicated in Wilson-Turner syndrome. Is an ortholog of human LAS1L (LAS1 like ribosome biogenesis factor).
- Tl [Search on AGR]
Drosophila melanogaster Toll (Tl) encodes a transmembrane receptor that activates the Tl intracellular signaling pathway upon binding the ligand encoded by spz. It is involved in dorso-ventral embryonic patterning and immunity.
- cogc-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Used to study Saul-Wilson syndrome. Human ortholog(s) of this gene implicated in Saul-Wilson syndrome and congenital disorder of glycosylation type IIj. Is an ortholog of human COG4 (component of oligomeric golgi complex 4).
- TEX41 [Search on AGR]
Homo sapiens ASSOCIATED WITH atrial fibrillation; Mowat-Wilson syndrome; INTERACTS WITH (+)-catechin; 4,4'-sulfonyldiphenol; bisphenol A
- Tehao [Search on AGR]
Drosophila melanogaster Tehao (Tehao) encodes a homologue of the receptor encoded by Tl. It is involved in the Toll signaling pathway and innate immune response.
- tey [Search on AGR]
Drosophila melanogaster teyrha-meyrha (tey) encodes a nuclear protein that regulates neuromuscular target specificity partly by repressing the expression of Tl in specific muscles.
- Pnpla7 [Search on AGR]
Homo sapiens Human patatin-like phospholipases, such as PNPLA7, have been implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson et al., 2006 [PubMed 16799181]).[supplied by OMIM, Jun 2008]
- snk [Search on AGR]
Drosophila melanogaster snake (snk) encodes a secreted serine protease. It is a member of the protease cascade that generates the ligand that activates the receptor encoded by Tl. It contributes to establishment of the dorsal-ventral embryonic axis.