sop-3

Caenorhabditis elegans

Predicted to be located in nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and neurons.

meg-4

Caenorhabditis elegans

Involved in P granule assembly; germ cell proliferation; and organelle localization. Located in P granule. Expressed in pharynx.

C27F2.4

Caenorhabditis elegans

Predicted to enable rRNA (guanine) methyltransferase activity. Predicted to be involved in rRNA (guanine-N7)-methylation. Predicted to be located in nucleolus. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Is an ortholog of human BUD23 (BUD23 rRNA methyltransferase and ribosome maturation factor).

drr-2

Caenorhabditis elegans

Predicted to enable RNA binding activity. Part of eukaryotic 48S preinitiation complex. Expressed in several structures, including coelomocyte; excretory canal; neurons; ventral nerve cord; and vulva. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Is an ortholog of human EIF4H (eukaryotic translation initiation factor 4H).

set-1

Caenorhabditis elegans

Predicted to enable RNA binding activity and histone H4K20 methyltransferase activity. Involved in embryo development. Located in nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human KMT5A (lysine methyltransferase 5A).

oef-1

Caenorhabditis elegans

Expressed in P lineage cell; germ cell; and oocyte.

nsun-1

Caenorhabditis elegans

Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in several processes, including negative regulation of cellular response to heat; negative regulation of locomotion involved in locomotory behavior; and positive regulation of reproductive process. Predicted to be located in nucleolus. Expressed widely. Used to study Williams-Beuren syndrome. Is an ortholog of human NOP2 (NOP2 nucleolar protein).

R107.2

Caenorhabditis elegans

Predicted to enable ATP-dependent NAD(P)H-hydrate dehydratase activity. Predicted to be involved in metabolite repair. Is an ortholog of human NAXD (NAD(P)HX dehydratase).

Y62E10A.24

Caenorhabditis elegans

Predicted to enable nucleic acid binding activity and ribonuclease P activity. Predicted to be involved in tRNA processing. Predicted to be located in nucleus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Is an ortholog of human POP7 (POP7 homolog, ribonuclease P/MRP subunit).

acds-10

Caenorhabditis elegans

Predicted to enable acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be located in cytoplasm. Expressed in P3.p hermaphrodite; P4.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human ACAD10 (acyl-CoA dehydrogenase family member 10).