PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased anxiety response in an open field test and increased startle response when treated with MK-801. [provided by MGI curators]
Enables phosphatidylinositol-3-phosphate binding activity. Involved in endocytosis. Located in early endosome and endocytic vesicle. Expressed in hypodermis and intestine. Is an ortholog of human EEA1 (early endosome antigen 1).