- Piezo2 [Search on AGR]
Homo sapiens The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
- Enam [Search on AGR]
Mus musculus PHENOTYPE: Homozygous null mice lack true enamel due to loss of mineralization at the secretory surface of ameloblasts and mandibular incisors are opaque with a rough surface and abnormal wear on the incisal edge. ENU-induced mutant mice provide models for various clinical subtypes of amelogenesis imperfecta. [provided by MGI curators]
- Ltw6 [Search on AGR]
Mus musculus PHENOTYPE: One of many loci showing variation in liver cytosol polypeptides detected by high resolution 2D electrophoresis. Allele a is present in most strains; allele b is found in strains SWR/J, BUB, PL, and MA/My. [provided by MGI curators]
- Gpt [Search on AGR]
Mus musculus PHENOTYPE: Electrophoretic variants are detected in C57BL/6, BALB/c and DBA/2 (a allele); in MA/J and NZB/Bl (b allele). M. m. molossinus and M. m. castaneus have either the b or c allele. In liver, GPT1 activity rises dramatically at 12-19 days to adult levels. [provided by MGI curators]
- Ly11 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls an antigen on T-cell subpopulations. The a allele determines absence of Ly11.2 antigen in A/J, BALB/c, C3H/DiSn, CE, NZB, CBA/J and SWR. The b allele determines antigen presence in C57 strains, AKR, C58, DBA/2, SJL, 129, PL and MA/My. [provided by MGI curators]
- Ly9 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls an antigen on thymocytes, lymphocytes and bone marrow cells. The a allele determines Ly9.1 antigen in A/J, 129/Re, BALB/c and C3H/He; the b allele determines antigen Ly9.2 in the C57 family of strains, HTI/Go, MA/My, F/St and C58/Lw. Null mutants are viable, healthy and fertile. [provided by MGI curators]
- Klrb1c [Search on AGR]
Mus musculus PHENOTYPE: This locus controls an antigen on natural killer cells. The a allele determines the Nk1.1 antigen in strains CE, C57BL/6, C57BR/cd, C57L, C58, DBA/1, MA/My, NZB, SJL, SM and B10.D2. The b allele determines the Nk1.2 antigen in strains CBA/J, BALB/c, C3H/He, A/J, DBA/2, LP and 129. [provided by MGI curators]
- Pnma5 [Search on AGR]
Homo sapiens This gene encodes a member of the paraneoplastic Ma antigen protein family. These proteins have been implicated in the development of paraneoplastic disorders resulting from an immune response directed against them. Paraneoplastic disorders are the result of an abnormal immune response to a tumor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2011]
- Jt1 [Search on AGR]
Mus musculus PHENOTYPE: AKR/J, C57BL/10, CBA/J, C3H/HeJ, C58/J, MA/My, MRL/Mp, RF/J, and B10.A(5R) strains carry the dominant b allele that allows expression of I-Jk antigen when in combination with H2k. CE/J and B10.A(3R) carry the a allele that does not allow expression of I-Jk in combination with H2k. [provided by MGI curators]
- GV1 [Search on AGR]
Mus musculus PHENOTYPE: Gv1 and Gv2 control GIX antigen on thymocytes of mice with positive alleles at both loci. Allele a (presence of GIX) is seen in 129, CE, AKR, SJL, DBA/2, C3H/An, 101, C58, A and I; allele b (absence) in C57BL strains, BALB/c, CBA/J, RF/J, MA/J and SWR. Heterozygotes have half the amount of antigen. [provided by MGI curators]