- Npy6r [Search on AGR]
Homo sapiens Predicted to enable pancreatic polypeptide receptor activity and peptide YY receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
- Pyy [Search on AGR]
Rattus norvegicus Predicted to enable neuropeptide Y receptor binding activity and neuropeptide hormone activity. Involved in negative regulation of response to food. Located in extracellular space. Orthologous to several human genes including PYY (peptide YY); INTERACTS WITH aldehydo-D-glucose; ammonium chloride; bisphenol A.
- Caps2 [Search on AGR]
Homo sapiens Calcyphosine-2 is a calcium-binding protein with 2 EF-hand motifs (Wang et al., 2002 [PubMed 11846421]).[supplied by OMIM, Mar 2008]
- Catsperg [Search on AGR]
Homo sapiens CATSPERG is a subunit of the CATSPER (see CATSPER1; MIM 606389) sperm calcium channel, which is required for sperm hyperactivated motility and male fertility (Wang et al., 2009 [PubMed 19516020]).[supplied by OMIM, Jul 2010]
- Utp20 [Search on AGR]
Homo sapiens UTP20 is a component of the U3 small nucleolar RNA (snoRNA) (SNORD3A; MIM 180710) protein complex (U3 snoRNP) and is involved in 18S rRNA processing (Wang et al., 2007 [PubMed 17498821]).[supplied by OMIM, Jun 2009]
- Ebf4 [Search on AGR]
Homo sapiens EBF4 belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, members of which play important roles in neural development and B-cell maturation (Wang et al., 2002 [PubMed 12139918]).[supplied by OMIM, Mar 2008]
- Pebp4 [Search on AGR]
Homo sapiens The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008]
- Npy1r [Search on AGR]
Homo sapiens This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]
- Npy5r [Search on AGR]
Homo sapiens The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015]
- Npy2r [Search on AGR]
Rattus norvegicus Enables peptide YY receptor activity. Involved in several processes, including negative regulation of cell communication; regulation of nervous system process; and regulation of secretion. Predicted to be located in non-motile cilium. Predicted to be active in cilium. Used to study childhood absence epilepsy and depressive disorder. Biomarker of obesity. Human ortholog(s) of this gene implicated in Huntington's disease; morbid obesity; and obesity. Orthologous to human NPY2R (neuropeptide Y receptor Y2); INTERACTS WITH 1D-myo-inositol 1,4,5-trisphosphate; ammonium chloride; bisphenol A.