Y22D7AL.11

Caenorhabditis elegans

Predicted to be involved in protein glycosylation. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin).

W02B3.7

Caenorhabditis elegans

Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin).

T07A5.1

Caenorhabditis elegans

Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin).

W02B3.4

Caenorhabditis elegans

Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin).

T07D3.4

Caenorhabditis elegans

Predicted to be involved in protein glycosylation. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin).

Ak6

Homo sapiens

This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

figl-1

Caenorhabditis elegans

Enables ATP hydrolysis activity; magnesium ion binding activity; and microtubule binding activity. Involved in ATP metabolic process and positive regulation of mitotic cell cycle. Located in nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in nicotine dependence. Is an ortholog of human FIGNL1 (fidgetin like 1).

Crppa

Homo sapiens

This gene encodes a 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein. Mutations in this gene are the cause of Walker-Warburg syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

Pomt2

Homo sapiens

The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS).[provided by RefSeq, Oct 2008]

Msh2

Saccharomyces cerevisiae

Protein that binds to DNA mismatches; forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity and involved in interstrand cross-link repair; Msh2p-Msh6p binds to and hydrolyzes ATP; required for silencing at the silent mating-type loci and telomeres