- rft-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables riboflavin transmembrane transporter activity. Involved in embryo development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A2 (solute carrier family 52 member 2) and SLC52A3 (solute carrier family 52 member 3).
- rft-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables riboflavin transmembrane transporter activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A1 (solute carrier family 52 member 1); SLC52A2 (solute carrier family 52 member 2); and SLC52A3 (solute carrier family 52 member 3).
- Scarf2 [Search on AGR]
Rattus norvegicus Predicted to enable scavenger receptor activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to act upstream of or within vesicle-mediated transport. Human ortholog(s) of this gene implicated in Van den Ende-Gupta syndrome. Orthologous to human SCARF2 (scavenger receptor class F member 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
- Zfp746 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a null allele show decreased incidence of DEN-induced liver tumors. [provided by MGI curators]
- Mgat3 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a null allele exhibit reduced DEN and PB-induced hepatic tumors and reduced hepatocyte proliferation. [provided by MGI curators]
- Acot12 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a null allele exhibit accelerated liver tumor formation in DEN/CCl4-induced and diet-induced hepatocarcinogenesis. [provided by MGI curators]
- CIR2 [Search on AGR]
Saccharomyces cerevisiae Putative ortholog of human ETF-dH; found in a large supramolecular complex with other mitochondrial dehydrogenases; may have a role in oxidative stress response; ETF-dH is also known as electron transfer flavoprotein dehydrogenase