rft-1

Caenorhabditis elegans

Enables riboflavin transmembrane transporter activity. Involved in embryo development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A2 (solute carrier family 52 member 2) and SLC52A3 (solute carrier family 52 member 3).

rft-2

Caenorhabditis elegans

Enables riboflavin transmembrane transporter activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A1 (solute carrier family 52 member 1); SLC52A2 (solute carrier family 52 member 2); and SLC52A3 (solute carrier family 52 member 3).

sop-3

Caenorhabditis elegans

Predicted to be located in nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and neurons.

meg-4

Caenorhabditis elegans

Involved in P granule assembly; germ cell proliferation; and organelle localization. Located in P granule. Expressed in pharynx.

set-1

Caenorhabditis elegans

Predicted to enable RNA binding activity and histone H4K20 methyltransferase activity. Involved in embryo development. Located in nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human KMT5A (lysine methyltransferase 5A).

oef-1

Caenorhabditis elegans

Expressed in P lineage cell; germ cell; and oocyte.

GRHL3-AS1

Homo sapiens

ASSOCIATED WITH Van der Woude Syndrome 2

R107.2

Caenorhabditis elegans

Predicted to enable ATP-dependent NAD(P)H-hydrate dehydratase activity. Predicted to be involved in metabolite repair. Is an ortholog of human NAXD (NAD(P)HX dehydratase).

paic-1

Caenorhabditis elegans

Enables identical protein binding activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase).

adss-1

Caenorhabditis elegans

Predicted to enable adenylosuccinate synthase activity. Predicted to be involved in 'de novo' AMP biosynthetic process and IMP metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ADSS1 (adenylosuccinate synthase 1).