spat-1

Caenorhabditis elegans

Predicted to enable protein kinase binding activity. Involved in positive regulation of mitotic cell cycle. Located in cytoplasm; kinetochore; and nucleus. Expressed in EMS and P2. Is an ortholog of human BORA (BORA aurora kinase A activator).

bora

Drosophila melanogaster

aurora borealis (bora) encodes a binding partner of the product of aurA. It is required for spindle orientation and asymmetric cell division.

bora

Rattus norvegicus

Predicted to enable protein kinase binding activity. Predicted to be involved in regulation of mitotic nuclear division; regulation of mitotic spindle organization; and regulation of protein localization. Predicted to be located in meiotic spindle. Predicted to be active in cytoplasm and nucleus. Orthologous to human BORA (BORA aurora kinase A activator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acetamide.

bora

Homo sapiens

BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM, Mar 2008]