uri-1

Caenorhabditis elegans

Predicted to enable chromatin binding activity; phosphatase inhibitor activity; and transcription corepressor activity. Involved in several processes, including germ-line stem cell division; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and regulation of cell cycle. Predicted to be located in nucleus. Expressed in germ line. Is an ortholog of human URI1 (URI1 prefoldin like chaperone).

SRAE_2000135000

Strongyloides ratti

Is predicted to encode a protein with the following domains: Tox-URI2 domain and URI fold toxin 2.

Cbn-uri-1

Caenorhabditis brenneri

Is predicted to encode a protein with the following domains: Prefoldin; Prefoldin alpha-like; and Prefoldin subunit. Is an ortholog of C. elegans uri-1. In C. elegans, uri-1 is involved in several processes, including germ-line stem cell division; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and regulation of cell cycle.

Cre-uri-1

Caenorhabditis remanei

Is predicted to encode a protein with the following domains: Prefoldin alpha-like and Prefoldin subunit. Is an ortholog of C. elegans uri-1. In C. elegans, uri-1 is involved in several processes, including germ-line stem cell division; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and regulation of cell cycle.

Cjp-uri-1

Caenorhabditis japonica

Is predicted to encode a protein with the following domains: Prefoldin; Prefoldin alpha-like; and Prefoldin subunit. Is an ortholog of C. elegans uri-1. In C. elegans, uri-1 is involved in several processes, including germ-line stem cell division; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and regulation of cell cycle.

Cbr-uri-1

Caenorhabditis briggsae

Is predicted to encode a protein with the following domains: Prefoldin; Prefoldin alpha-like; and Prefoldin subunit. Is an ortholog of C. elegans uri-1. In C. elegans, uri-1 is involved in several processes, including germ-line stem cell division; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and regulation of cell cycle.

BUD27

Saccharomyces cerevisiae

Unconventional prefoldin protein involved in translation initiation; required for correct assembly of RNAP I, II, and III in an Rpb5p-dependent manner; shuttles between nucleus and cytoplasm; mutants have inappropriate expression of nutrient sensitive genes due to translational derepression of Gcn4p transcription factor; diploid mutants show random budding; mutations affect TOR signaling; ortholog of human URI/RMP