ant-1.2

Caenorhabditis elegans

Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Located in mitochondrion. Expressed in body wall musculature; head neurons; intestine; pharynx; and seam cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6).

ant-1.3

Caenorhabditis elegans

Predicted to enable adenine nucleotide transmembrane transporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Expressed in VA11 and intestine. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A5 (solute carrier family 25 member 5) and SLC25A6 (solute carrier family 25 member 6).

ant-1.4

Caenorhabditis elegans

Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Located in mitochondrion. Expressed in amphid sensillum; body wall musculature; rectal gland cell; somatic nervous system; and vulval muscle. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6).

ant-1.1

Caenorhabditis elegans

Predicted to enable ATP:ADP antiporter activity. Involved in determination of adult lifespan; mitochondrion organization; and positive regulation of apoptotic process. Located in mitochondrion. Expressed in several structures, including body wall musculature; hermaphrodite somatic gonadal cell; intestine; pharynx; and vulva. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6).

C03B1.6

Caenorhabditis elegans

Enriched in OLQ; arc ant V; and neurons based on tiling array; single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including cyc-1; etr-1; and csr-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

K04A8.20

Caenorhabditis elegans

Enriched in arc ant V; head mesodermal cell; hyp3; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cua-1; atfs-1; and rrf-3 based on RNA-seq studies. Is affected by eight chemicals including D-glucopyranose; Alovudine; and metformin based on RNA-seq studies.

F35A5.5

Caenorhabditis elegans

Enriched in arc ant V; hyp1; and hyp2 based on single-cell RNA-seq studies. Is affected by several genes including nuo-6; atfs-1; and etr-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; D-glucose; and stavudine based on microarray and RNA-seq studies.

F09A5.3

Caenorhabditis elegans

Enriched in anterior hypodermis; arc ant V; excretory gland cell; intestine; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cyc-1; etr-1; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and rifampin based on RNA-seq and microarray studies.

Y65B4BL.6

Caenorhabditis elegans

Enriched in anterior hypodermis; arc ant V; rectal epithelial cell; and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including cyc-1; nuo-6; and atfs-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Ethanol; tryptophan; and 1-methylnicotinamide based on RNA-seq and microarray studies.

C34D4.10

Caenorhabditis elegans

Enriched in arc ant V; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cua-1; atfs-1; and etr-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies.