YNL017C

Saccharomyces cerevisiae

Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the tRNA ORF tI(AAU)N2

Lyb7

Mus musculus

PHENOTYPE: This locus controls antigen present on a subset of mature B lymphocytes. Anti-Lyb7.1 blocks in vitro response to TNP-Ficoll and some TI-2 antigens. DBA/2 and C3H/He are susceptible to anti-Ly7.1 antibody block; C57BL/6 and AL/N are not susceptible. Heterozygotes are susceptible. [provided by MGI curators]

sinu

Drosophila melanogaster

sinuous (sinu) encodes a claudin that contributes to the assembly of septate junctions. It is involved in the development of heart, tracheal tree and the glial blood-brain barrier.

hpc

Mus musculus

PHENOTYPE: Mice homozygous for a chemically-induced allele are sterile and growth retarded, show a reduced cerebellar cortex, hyperspiny Purkinje cells, an atrophic dendritic tree and signs of axonal degeneration, and develop a fatal disease characterized by abnormal motor behavior and cerebellar symptoms. [provided by MGI curators]

Elovl5

Rattus norvegicus

Enables fatty acid elongase activity. Involved in fatty acid elongation, polyunsaturated fatty acid and very long-chain fatty acid biosynthetic process. Predicted to be located in dendritic tree; endoplasmic reticulum; and neuronal cell body. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 38. Orthologous to human ELOVL5 (ELOVL fatty acid elongase 5); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.