kin-18

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Involved in feeding behavior; regulation of meiosis I; and regulation of nematode pharyngeal pumping. Located in cell cortex. Expressed in several structures, including alimentary muscle; excretory cell; intestine; nerve ring; and pharyngeal-intestinal valve. Is an ortholog of human TAOK1 (TAO kinase 1); TAOK2 (TAO kinase 2); and TAOK3 (TAO kinase 3).

B0272.4

Caenorhabditis elegans

Predicted to enable delta(3)-delta(2)-enoyl-CoA isomerase activity. Predicted to be located in peroxisome. Expressed widely. Is an ortholog of several human genes including CDY1 (chromodomain Y-linked 1); CDY2A (chromodomain Y-linked 2A); and CDYL (chromodomain Y like).

npr-12

Caenorhabditis elegans

Predicted to enable neuropeptide Y receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in FLPL; FLPR; PVDL; and PVDR. Human ortholog(s) of this gene implicated in several diseases, including amphetamine abuse; cocaine abuse; and heroin dependence. Is an ortholog of human NPY1R (neuropeptide Y receptor Y1); NPY4R (neuropeptide Y receptor Y4); and NPY4R2 (neuropeptide Y receptor Y4-2).

cyy-1

Caenorhabditis elegans

Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity. Involved in negative regulation of synapse assembly; regulation of neuron remodeling; and regulation of terminal button organization. Located in axon and dendrite. Is an ortholog of human CCNY (cyclin Y) and CCNYL1 (cyclin Y like 1).

cey-4

Caenorhabditis elegans

Enables ribonucleoprotein complex binding activity. Predicted to be involved in regulation of gene expression. Part of ribonucleoprotein complex. Expressed in germ cell; germ line; and somatic cell. Is an ortholog of human YBX1 (Y-box binding protein 1) and YBX2 (Y-box binding protein 2).

npr-8

Caenorhabditis elegans

Predicted to enable neuropeptide Y receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane.

his-70

Caenorhabditis elegans

Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed in sperm. Is an ortholog of human H3Y1 (H3.Y histone 1) and H3Y2 (H3.Y histone 2).

npr-11

Caenorhabditis elegans

Predicted to enable neuropeptide Y receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. Expressed in neurons and tail neurons.

Tao

Drosophila melanogaster

Tao (Tao) encodes a Ser/Thr kinase belonging to the Mst/Ste20 family. It is implicated in the Hippo and PAR-1 pathways. It contributes to restriction of tissue growth during development, regulation of microtubule dynamics, neuronal polarity, neural development, ethanol-stimulated behavioral response, and apoptosis.

rps-4

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS4X (ribosomal protein S4 X-linked); RPS4Y1 (ribosomal protein S4 Y-linked 1); and RPS4Y2 (ribosomal protein S4 Y-linked 2).