Predicted to enable ubiquitin protein ligase activity. Involved in chromosome segregation; negative regulation of vulval development; and transcription initiation-coupled chromatin remodeling. Located in germ cell nucleus. Expressed in several structures, including germ line.
Predicted to enable ATP hydrolysis activity; chromatin binding activity; and histone binding activity. Involved in regulation of heterochromatin formation. Predicted to be located in nucleus. Is an ortholog of human ATAD2 (ATPase family AAA domain containing 2) and ATAD2B (ATPase family AAA domain containing 2B).
Is an ortholog of C. elegans tam-1. In C. elegans, tam-1 is involved in chromosome segregation; negative regulation of vulval development; and transcription initiation-coupled chromatin remodeling.
Predicted to enable inward rectifier potassium channel activity. Involved in short-term memory. Predicted to be located in plasma membrane. Predicted to be part of monoatomic ion channel complex. Expressed in HSNL; HSNR; and sensory neurons. Human ortholog(s) of this gene implicated in several diseases, including Bartter disease type 2; EAST syndrome; and Leber congenital amaurosis 16. Is an ortholog of human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10); KCNJ13 (potassium inwardly rectifying channel subfamily J member 13); and KCNJ15 (potassium inwardly rectifying channel subfamily J member 15).
Enables inward rectifier potassium channel activity. Involved in regulation of G protein-coupled receptor signaling pathway and regulation of egg-laying behavior. Located in neuron projection and neuronal cell body. Expressed in egg-laying apparatus; gonad; intestine; and neurons. Human ortholog(s) of this gene implicated in several diseases, including glucose metabolism disease (multiple); heart conduction disease (multiple); and long QT syndrome (multiple). Is an ortholog of several human genes including KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); KCNJ3 (potassium inwardly rectifying channel subfamily J member 3); and KCNJ4 (potassium inwardly rectifying channel subfamily J member 4).