ASPP [Search on AGR]
Drosophila melanogaster Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein (ASPP) encodes a scaffold protein localised at the adherens junctions (AJ) of epithelial cells. It promotes AJ stability by repressing Src activity via the kinase encoded by Csk.
Pogz [Search on AGR]
Rattus norvegicus Predicted to enable metal ion binding activity and nucleic acid binding activity. Predicted to be involved in kinetochore assembly and mitotic sister chromatid cohesion. Predicted to act upstream of or within with a positive effect on double-strand break repair via homologous recombination. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of chromatin. Human ortholog(s) of this gene implicated in White-Sutton syndrome. Orthologous to human POGZ (pogo transposable element derived with ZNF domain); INTERACTS WITH 2,6-dinitrotoluene; amitrole; bisphenol A.