sun-1

Caenorhabditis elegans

Predicted to enable protein-membrane adaptor activity. Involved in several processes, including centrosome localization; embryo development; and regulation of centrosome duplication. Located in nuclear envelope. Expressed in several structures, including Caa; Psub4; Z2; Z3; and germ line. Human ortholog(s) of this gene implicated in spermatogenic failure 16. Is an ortholog of human SUN5 (Sad1 and UNC84 domain containing 5).

suco-1

Caenorhabditis elegans

Predicted to be located in cytoplasm and membrane. Expressed widely. Is an ortholog of human SUCO (SUN domain containing ossification factor).

kdp-1

Caenorhabditis elegans

Located in cytoplasm and nuclear envelope. Used to study muscular dystrophy.

unc-84

Caenorhabditis elegans

Enables lamin binding activity. Involved in several processes, including egg-laying behavior; nuclear migration along microtubule; and vulval development. Located in nuclear inner membrane. Expressed in several structures, including oocyte. Human ortholog(s) of this gene implicated in spermatogenic failure 16. Is an ortholog of human SUN2 (Sad1 and UNC84 domain containing 2) and SUN3 (Sad1 and UNC84 domain containing 3).

srw-135

Caenorhabditis elegans

Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway.

npr-41

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of human GPR142 (G protein-coupled receptor 142).

srw-85

Caenorhabditis elegans

Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Expressed in neurons.

mth-2

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in X-linked congenital bilateral absence of vas deferens and vibratory urticaria. Is an ortholog of human ADGRE2 (adhesion G protein-coupled receptor E2); ADGRG2 (adhesion G protein-coupled receptor G2); and ADGRG7 (adhesion G protein-coupled receptor G7).

nsun-5

Caenorhabditis elegans

Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in several processes, including negative regulation of cellular response to heat; negative regulation of locomotion involved in locomotory behavior; and positive regulation of rRNA processing. Predicted to be located in nucleolus. Used to study Williams-Beuren syndrome. Is an ortholog of human NSUN5 (NOP2/Sun RNA methyltransferase 5).

frpr-8

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane.