sun-1

Caenorhabditis elegans

Predicted to enable protein-membrane adaptor activity. Involved in several processes, including centrosome localization; embryo development; and regulation of centrosome duplication. Located in nuclear envelope. Expressed in several structures, including Caa; Psub4; Z2; Z3; and germ line. Human ortholog(s) of this gene implicated in spermatogenic failure 16. Is an ortholog of human SUN5 (Sad1 and UNC84 domain containing 5).

suco-1

Caenorhabditis elegans

Predicted to be located in cytoplasm and membrane. Expressed widely. Is an ortholog of human SUCO (SUN domain containing ossification factor).

kdp-1

Caenorhabditis elegans

Located in cytoplasm and nuclear envelope. Used to study muscular dystrophy.

sdz-26

Caenorhabditis elegans

Expressed in E; Ea; and Ep.

unc-84

Caenorhabditis elegans

Enables lamin binding activity. Involved in several processes, including egg-laying behavior; nuclear migration along microtubule; and vulval development. Located in nuclear inner membrane. Expressed in several structures, including oocyte. Human ortholog(s) of this gene implicated in spermatogenic failure 16. Is an ortholog of human SUN2 (Sad1 and UNC84 domain containing 2) and SUN3 (Sad1 and UNC84 domain containing 3).

nsun-5

Caenorhabditis elegans

Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in several processes, including negative regulation of cellular response to heat; negative regulation of locomotion involved in locomotory behavior; and positive regulation of rRNA processing. Predicted to be located in nucleolus. Used to study Williams-Beuren syndrome. Is an ortholog of human NSUN5 (NOP2/Sun RNA methyltransferase 5).

sdz-23

Caenorhabditis elegans

Predicted to enable Notch binding activity. Predicted to be located in membrane. Expressed in E; Ea; and Ep.

pges-2

Caenorhabditis elegans

Predicted to enable prostaglandin-E synthase activity. Predicted to be involved in prostaglandin biosynthetic process. Predicted to be located in mitochondrion. Expressed in hypodermis; intestinal cell; lumbar ganglion; muscle cell; and retrovesicular ganglion. Is an ortholog of human PTGES2 (prostaglandin E synthase 2).

sdz-1

Caenorhabditis elegans

Involved in mesendoderm development. Expressed in several structures, including E; Ea; Ep; MSpa; and somatic gonad precursor.

eif-3.E

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in nucleus. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in head and tail. Is an ortholog of human EIF3E (eukaryotic translation initiation factor 3 subunit E).