Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in positive regulation of translation. Predicted to be located in cytoplasmic stress granule and cytosol. Expressed in PVDL; PVDR; and neurons. Is an ortholog of human LARP4 (La ribonucleoprotein 4) and LARP4B (La ribonucleoprotein 4B).
Enables poly(G) binding activity and poly(U) RNA binding activity. Predicted to be involved in positive regulation of translation. Located in P-body. Expressed in germ line; head; and tail. Is an ortholog of human LARP1 (La ribonucleoprotein 1, translational regulator) and LARP1B (La ribonucleoprotein 1B).
Predicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in tryptophan catabolic process to acetyl-CoA. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Is an ortholog of human TDO2 (tryptophan 2,3-dioxygenase).
Predicted to enable mRNA binding activity. Predicted to be involved in positive regulation of translation and tRNA processing. Predicted to be located in cytoplasmic stress granule; cytosol; and nucleus. Predicted to be part of ribonucleoprotein complex. Expressed in head and tail. Is an ortholog of human SSB (small RNA binding exonuclease protection factor La).
This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]
Is predicted to encode a protein with the following domains: La domain; Winged helix DNA-binding domain superfamily; La-type HTH domain; and Winged helix-like DNA-binding domain superfamily.
Is predicted to encode a protein with the following domains: La domain; Winged helix DNA-binding domain superfamily; La-type HTH domain; and Winged helix-like DNA-binding domain superfamily.
Is predicted to encode a protein with the following domains: La domain; Winged helix DNA-binding domain superfamily; La-type HTH domain; and Winged helix-like DNA-binding domain superfamily. Is an ortholog of C. elegans larp-5.
Is predicted to encode a protein with the following domains: La domain; Winged helix DNA-binding domain superfamily; La-type HTH domain; and Winged helix-like DNA-binding domain superfamily. Is an ortholog of C. elegans larp-5.