- Ltw3 [Search on AGR]
Mus musculus PHENOTYPE: One of many loci showing variation in liver cytosol polypeptides detected by high resolution 2D electrophoresis. Allele a encodes a more acidic protein in BALB/c, C3H/He, DBA/2, A/J, AKR/J; allele b encodes a more basic protein in C57BL6, C3H/St, AU/SsJ. [provided by MGI curators]
- irk-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable inward rectifier potassium channel activity. Involved in short-term memory. Predicted to be located in plasma membrane. Predicted to be part of monoatomic ion channel complex. Expressed in HSNL; HSNR; and sensory neurons. Human ortholog(s) of this gene implicated in several diseases, including Bartter disease type 2; EAST syndrome; and Leber congenital amaurosis 16. Is an ortholog of human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10); KCNJ13 (potassium inwardly rectifying channel subfamily J member 13); and KCNJ15 (potassium inwardly rectifying channel subfamily J member 15).
- Pepc [Search on AGR]
Mus musculus PHENOTYPE: Electrophoretic variants of red blood cell PEPC are: C57BL/6 has a slow anodal band (a allele); CBA/J and A/He, a faster band (b allele); NZB, ST/b and RIIIS/J, an even faster band (c allele). Heterozygotes have both bands. Mice homozygous for ENU or procarbazine induced null alleles are viable. [provided by MGI curators]
- irk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables inward rectifier potassium channel activity. Involved in regulation of G protein-coupled receptor signaling pathway and regulation of egg-laying behavior. Located in neuron projection and neuronal cell body. Expressed in egg-laying apparatus; gonad; intestine; and neurons. Human ortholog(s) of this gene implicated in several diseases, including glucose metabolism disease (multiple); heart conduction disease (multiple); and long QT syndrome (multiple). Is an ortholog of several human genes including KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); KCNJ3 (potassium inwardly rectifying channel subfamily J member 3); and KCNJ4 (potassium inwardly rectifying channel subfamily J member 4).
- Epa1 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls presence or absence of an epidermal antigen inducing CTL in H2 compatible hosts lacking the antigen. Antigen is present in AKR, BALB/c, CBA/J, C3H/Bi, C57BL and DBA; and absent in C3H/He, C3H/An, A/J, A/He, LG and ST/b. This locus also acts like a minor histocompatibility locus. [provided by MGI curators]