Predicted to enable metal ion binding activity. Involved in lysosome organization. Predicted to be located in endosome. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 6. Is an ortholog of human PLEKHM1 (pleckstrin homology and RUN domain containing M1).
Enables small GTPase binding activity. Involved in several processes, including dense core granule maturation; positive regulation of behavior; and regulation of transport. Located in several cellular components, including Golgi trans cisterna; neuronal cell body; and perinuclear region of cytoplasm. Expressed in uterus. Is an ortholog of human RUNDC1 (RUN domain containing 1).
Is predicted to encode a protein with the following domains: SH3 domain; SH3-like domain superfamily; RUN domain; RUN domain superfamily; and Homeobox-like domain superfamily.
Is predicted to encode a protein with the following domains: PDZ domain; RUN domain; RUN domain superfamily; and PDZ superfamily. Is an ortholog of C. elegans nrfl-1.
Is predicted to encode a protein with the following domains: Phosphotyrosine interaction domain (PTB/PID); PTB/PI domain; RUN domain; RUN domain superfamily; PDZ superfamily; and PH-like domain superfamily.
Enables protein kinase binding activity and scaffold protein binding activity. Involved in regulation of protein localization and synaptic vesicle localization. Located in neuron projection. Expressed in several structures, including hypodermis; intestine; motor neurons; muscle cell; and uterus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 61. Is an ortholog of human RUSC1 (RUN and SH3 domain containing 1) and RUSC2 (RUN and SH3 domain containing 2).
Is predicted to encode a protein with the following domains: Pleckstrin homology domain; PH domain; RUN domain; RUN domain superfamily; and PH-like domain superfamily. Is an ortholog of C. elegans T10B10.3.