Y37E3.1

Caenorhabditis elegans

Enriched in several structures, including ABalpppappp; ABalpppppa; ABalppppppp; ciliated neurons; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including hsf-1; srbc-48; and mrpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including rotenone; paraquat; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Tetratricopeptide repeat; Tetratricopeptide-like helical domain superfamily; Tetratricopeptide repeat protein 5, OB fold domain; Tetratricopeptide repeat protein 5 OB fold domain; and TTC5, OB fold domain superfamily. Is an ortholog of human TTC5 (tetratricopeptide repeat domain 5). Human TTC5 enables ribosome binding activity.

paic-1

Caenorhabditis elegans

Enables identical protein binding activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase).

adss-1

Caenorhabditis elegans

Predicted to enable adenylosuccinate synthase activity. Predicted to be involved in 'de novo' AMP biosynthetic process and IMP metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ADSS1 (adenylosuccinate synthase 1).

CBG26841

Caenorhabditis briggsae

Is predicted to encode a protein with the following domains: Nucleic acid-binding, OB-fold; Replication factor-A C terminal domain; Replication protein A, OB domain; Replication factor A, C-terminal; and Replication protein A OB domain.

tdo-2

Caenorhabditis elegans

Predicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in tryptophan catabolic process to acetyl-CoA. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Is an ortholog of human TDO2 (tryptophan 2,3-dioxygenase).

PPA39683

Pristionchus pacificus

Is predicted to encode a protein with the following domains: De-etiolated protein 1, Det1 and De-etiolated protein 1 Det1.

Bm6393

Brugia malayi

Is predicted to encode a protein with the following domains: Tetratricopeptide repeat protein 5, OB fold domain; Tetratricopeptide repeat protein 5 OB fold domain; TTC5, OB fold domain superfamily; and Tetratricopeptide-like helical domain superfamily. Is an ortholog of C. elegans Y37E3.1.

haao-1

Caenorhabditis elegans

Predicted to enable 3-hydroxyanthranilate 3,4-dioxygenase activity. Predicted to be involved in 'de novo' NAD biosynthetic process from tryptophan and quinolinate metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human HAAO (3-hydroxyanthranilate 3,4-dioxygenase).

CBN24569

Caenorhabditis brenneri

Is predicted to encode a protein with the following domains: Tetratricopeptide repeat; Tetratricopeptide-like helical domain superfamily; Tetratricopeptide repeat protein 5, OB fold domain; Tetratricopeptide repeat protein 5 OB fold domain; and TTC5, OB fold domain superfamily. Is an ortholog of C. elegans Y37E3.1.

OVOC6114

Onchocerca volvulus

Is predicted to encode a protein with the following domains: Tetratricopeptide repeat; Tetratricopeptide-like helical domain superfamily; Tetratricopeptide repeat protein 5, OB fold domain; Tetratricopeptide repeat protein 5 OB fold domain; and TTC5, OB fold domain superfamily. Is an ortholog of C. elegans Y37E3.1.