This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins and NT-type C2 domain. Is an ortholog of C. elegans sym-3.
Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins; Protein FAM102-like; and NT-type C2 domain. Is an ortholog of C. elegans sym-3.
Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins; Protein FAM102-like; and NT-type C2 domain. Is an ortholog of C. elegans sym-3.
Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins; Protein FAM102-like; and NT-type C2 domain. Is an ortholog of C. elegans sym-3.
Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins; Protein FAM102-like; and NT-type C2 domain. Is an ortholog of C. elegans sym-3.
Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins; Protein FAM102-like; and NT-type C2 domain. Is an ortholog of C. elegans sym-3.
Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins; Protein FAM102-like; and NT-type C2 domain. Is an ortholog of C. elegans sym-3.
Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins; Protein FAM102-like; and NT-type C2 domain. Is an ortholog of C. elegans sym-3.
Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins; Protein FAM102-like; and NT-type C2 domain. Is an ortholog of C. elegans sym-3.