- C21orf58 [Search on AGR]
Homo sapiens ASSOCIATED WITH Autism; autistic disorder; Axenfeld-Rieger syndrome type 3; INTERACTS WITH 1,2-dichloroethane; 17beta-estradiol; acrylamide
- LINC00163 [Search on AGR]
Homo sapiens ASSOCIATED WITH Autism; autistic disorder; Axenfeld-Rieger syndrome type 3; INTERACTS WITH aristolochic acid A; arsenite(3-); malathion
- LINC00334 [Search on AGR]
Homo sapiens ASSOCIATED WITH Autism; autistic disorder; Axenfeld-Rieger syndrome type 3; INTERACTS WITH aristolochic acid A; rotenone; silicon dioxide
- LINC00315 [Search on AGR]
Homo sapiens ASSOCIATED WITH Axenfeld-Rieger syndrome type 3; cataract 9 multiple types; developmental and epileptic encephalopathy 30; INTERACTS WITH resveratrol
- Fras1 [Search on AGR]
Homo sapiens ENCODES an gene that exhibits metal ion binding (inferred); INVOLVED IN embryonic limb morphogenesis (ortholog); metanephros morphogenesis (ortholog); morphogenesis of an epithelium (ortholog); ASSOCIATED WITH Axenfeld-Rieger syndrome; CAKUT; Congenital diaphragmatic hernia; FOUND IN basement membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2-methylcholine; 4,4'-sulfonyldiphenol
- Foxc1 [Search on AGR]
Rattus norvegicus Predicted to enable several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and promoter-specific chromatin binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell differentiation; and regulation of gene expression. Predicted to act upstream of or within several processes, including cell surface receptor signaling pathway; circulatory system development; and collagen fibril organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of heterochromatin. Human ortholog(s) of this gene implicated in Axenfeld-Rieger syndrome; Axenfeld-Rieger syndrome type 3; anterior segment dysgenesis 3; and glaucoma. Orthologous to human FOXC1 (forkhead box C1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
- Pitx2 [Search on AGR]
Rattus norvegicus Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including gonad development; positive regulation of transcription by RNA polymerase II; and response to vitamin A. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Biomarker of autosomal dominant polycystic kidney disease and hypothyroidism. Human ortholog(s) of this gene implicated in Arts syndrome; Axenfeld-Rieger syndrome; Axenfeld-Rieger syndrome type 1; anterior segment dysgenesis 4; and ring dermoid of cornea. Orthologous to human PITX2 (paired like homeodomain 2); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.