K10D2.8

Caenorhabditis elegans

Enriched in head mesodermal cell and in male based on RNA-seq studies. Is affected by several genes including mut-16; etr-1; and csr-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine Rich repeat; Leucine Rich repeats (2 copies); Leucine-rich repeat; Leucine-rich repeat, typical subtype; Leucine rich repeat 4; Leucine-rich repeat domain superfamily; and Ciliary and flagellar integrity-associated protein.

lron-4

Caenorhabditis elegans

Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyc-1; nuo-6; and atfs-1 based on microarray; RNA-seq; and proteomic studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat; Leucine-rich repeat, typical subtype; Small Leucine-Rich Proteoglycans; Leucine rich repeat; and Leucine-rich repeat domain superfamily.

lrch-1

Caenorhabditis elegans

Predicted to be involved in signal transduction. Is an ortholog of several human genes including LRCH1 (leucine rich repeats and calponin homology domain containing 1); LRCH2 (leucine rich repeats and calponin homology domain containing 2); and LRCH4 (leucine rich repeats and calponin homology domain containing 4).

T05H4.3

Caenorhabditis elegans

Enriched in neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including etr-1; csr-1; and dpy-21 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: U2A'/phosphoprotein 32 family A, C-terminal; Leucine Rich repeats (2 copies); SDS22/Internalin LRR-containing; Leucine-rich repeat; Leucine-rich repeat, typical subtype; Leucine rich repeat 4; and Leucine-rich repeat domain superfamily. Is an ortholog of human LRRC9 (leucine rich repeat containing 9).

F19C7.8

Caenorhabditis elegans

Predicted to be involved in positive regulation of protein localization to plasma membrane and skeletal muscle contraction. Human ortholog(s) of this gene implicated in Native American myopathy. Is an ortholog of human STAC (SH3 and cysteine rich domain); STAC2 (SH3 and cysteine rich domain 2); and STAC3 (SH3 and cysteine rich domain 3).

K08E7.8

Caenorhabditis elegans

Enriched in intestine; muscle cell; and somatic gonad precursor based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including etr-1; hsf-1; and srbc-48 based on RNA-seq and microarray studies. Is affected by eight chemicals including Zidovudine; rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat; Leucine-rich repeat domain superfamily; Leucine-rich repeat domain-containing protein; and Leucine rich repeat. Is an ortholog of human LRRC20 (leucine rich repeat containing 20).

M05D6.2

Caenorhabditis elegans

Predicted to be involved in signal transduction. Is an ortholog of human TCP11 (t-complex 11); TCP11L1 (t-complex 11 like 1); and TCP11L2 (t-complex 11 like 2).

D2089.8

Caenorhabditis elegans

Enriched in dorsal uterine cell and germ line based on single-cell RNA-seq studies. Is affected by several genes including hsf-1; inx-14; and slr-2 based on RNA-seq and microarray studies. Is affected by four chemicals including antimycin; Hydrolyzable Tannins; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Cysteine-rich domain; Cysteine-rich domain, DPF-motif; and Cysteine-rich DPF motif domain-containing protein 1. Is an ortholog of human CDPF1 (cysteine rich DPF motif domain containing 1).

iglr-3

Caenorhabditis elegans

Predicted to be located in membrane. Is an ortholog of human LRRC24 (leucine rich repeat containing 24).

ZK546.2

Caenorhabditis elegans

Predicted to be located in cytoplasm. Is an ortholog of human LRRC57 (leucine rich repeat containing 57).