Prr30

Homo sapiens

ASSOCIATED WITH Tatton-Brown-Rahman syndrome; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; valproic acid

Ccdc121

Homo sapiens

ASSOCIATED WITH Tatton-Brown-Rahman syndrome; INTERACTS WITH 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol

Cgref1

Homo sapiens

ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH essential fructosuria; Tatton-Brown-Rahman syndrome; FOUND IN extracellular region (inferred); INTERACTS WITH (S)-nicotine; 2-palmitoylglycerol; acrylamide

Dnmt3a

Rattus norvegicus

Enables chromatin binding activity. Involved in several processes, including cellular response to ethanol; hepatocyte apoptotic process; and positive regulation of cellular response to hypoxia. Located in nucleus. Used to study lung carcinoma and middle cerebral artery infarction. Biomarker of congenital heart disease; hepatocellular carcinoma; and prostatitis. Human ortholog(s) of this gene implicated in Tatton-Brown-Rahman syndrome; hematologic cancer (multiple); and stomach cancer. Orthologous to human DNMT3A (DNA methyltransferase 3 alpha); PARTICIPATES IN DNA modification pathway; methionine cycle/metabolic pathway; cysteine and methionine metabolic pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17alpha-ethynylestradiol.