pes-5

Caenorhabditis elegans

Predicted to be located in membrane.

Y52E8A.6

Caenorhabditis elegans

Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11).

YKL069W

Saccharomyces cerevisiae

Methionine-R-sulfoxide reductase; reduces the R enantiomer of free Met-SO, in contrast to Ycl033Cp which reduces Met-R-SO in a peptide linkage; has a role in protection against oxidative stress; capable of binding and degrading patulin, a polyketide mycotoxin, forming E-ascladiol; relative distribution to the nucleus increases upon DNA replication stress

mud-1

Caenorhabditis elegans

Y39C12A.2

Caenorhabditis elegans

Enriched in dorsal uterine cell; hypodermis; and interfacial epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including hyl-1; etr-1; and lpd-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.

dac

Drosophila melanogaster

dachshund (dac) encodes a transcriptional cofactor that physically interacts with several other retinal determination proteins, including those encoded by eya and so, and regulates eye, leg, gonad, and brain development.

pnt

Drosophila melanogaster

pointed (pnt) encodes an ETS family transcriptional activator that functions downstream of Ras signaling. It is necessary and sufficient for triggering cellular senescence upon Ras activation, and by doing so suppresses Ras-driven tumor growth.

T25G3.3

Caenorhabditis elegans

Predicted to enable ribosomal large subunit binding activity. Predicted to be involved in ribosomal large subunit export from nucleus. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human NMD3 (NMD3 ribosome export adaptor).

Ecm2

Homo sapiens

ECM2 encodes extracellular matrix protein 2, so named because it shares extensive similarity with known extracelluar matrix proteins. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Pianp

Homo sapiens

This gene encodes a ligand for the paired immunoglobin-like type 2 receptor alpha, and so may be involved in immune regulation. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Sep 2011]