- W02F12.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 3'-5'-DNA exonuclease activity. Predicted to be involved in DNA catabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome; lupus erythematosus (multiple); and retinal vasculopathy with cerebral leukodystrophy. Is an ortholog of human TREX1 (three prime repair exonuclease 1) and TREX2 (three prime repair exonuclease 2).
- Y41C4A.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable zinc ion binding activity. Involved in endoplasmic reticulum unfolded protein response. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in endosome membrane and lysosomal membrane. Expressed in pharynx.
- F25B5.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 5'-nucleotidase activity. Predicted to be involved in nucleotide metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human NT5C3A (5'-nucleotidase, cytosolic IIIA).
- vep-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable TFIIIC-class transcription factor complex binding activity. Predicted to be involved in RNA polymerase III preinitiation complex assembly. Predicted to be part of transcription factor TFIIIB complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 112. Is an ortholog of human BDP1 (B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB).
- Bdp1 [Search on AGR]
Drosophila melanogaster B double prime 1 (Bdp1) encodes a transcription factor involved in snRNA gene transcription.
- Papss1 [Search on AGR]
Homo sapiens Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008]
- Hs3st5 [Search on AGR]
Homo sapiens HS3ST5 belongs to a group of heparan sulfate 3-O-sulfotransferases (EC 2.8.2.23) that transfer sulfate from 3-prime-phosphoadenosine 5-prime phosphosulfate (PAPS) to heparan sulfate and heparin (Mochizuki et al., 2003 [PubMed 12740361]).[supplied by OMIM, Mar 2008]
- Pde6c [Search on AGR]
Homo sapiens This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4). [provided by RefSeq, Mar 2010]
- RPO31 [Search on AGR]
Saccharomyces cerevisiae RNA polymerase III largest subunit C160; part of core enzyme; similar to bacterial beta-prime subunit and to RPA190 and RPO21
- Arp5 [Search on AGR]
Saccharomyces cerevisiae Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; promotes nucleosome shifts in the 3 prime direction