- che-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in chemosensory behavior; cilium organization; and protein localization. Located in axoneme; ciliary basal body; and ciliary transition zone. Part of intraciliary transport particle B. Expressed in neurons. Used to study ciliopathy. Human ortholog(s) of this gene implicated in orofaciodigital syndrome. Is an ortholog of human IFT57 (intraflagellar transport 57).
- che-12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable microtubule binding activity. Involved in several processes, including chemotaxis; cilium assembly; and hyperosmotic response. Located in cilium; dendrite; and neuronal cell body. Expressed in amphid neurons and phasmid neurons. Used to study ciliopathy. Human ortholog(s) of this gene implicated in Joubert syndrome. Is an ortholog of human TOGARAM1 (TOG array regulator of axonemal microtubules 1) and TOGARAM2 (TOG array regulator of axonemal microtubules 2).
- che-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including response to alkaline pH; response to metal ion; and response to methionine. Predicted to be located in nucleus. Expressed in ASEL and ASER.
- che-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in cilium assembly. Located in ciliary basal body and ciliary transition zone. Is an ortholog of human CEP250 (centrosomal protein 250) and CROCC (ciliary rootlet coiled-coil, rootletin).
- che-14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane transporter activity. Predicted to be involved in smoothened signaling pathway. Located in apical plasma membrane. Expressed in epithelial cell; excretory system; hypodermis; rectum; and vulva. Is an ortholog of human DISP1 (dispatched RND transporter family member 1) and DISP2 (dispatched RND transporter family member 2).
- che-11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in several processes, including dauer entry; positive regulation of intracellular transport; and response to stress. Located in non-motile cilium. Expressed in head and neurons. Human ortholog(s) of this gene implicated in retinitis pigmentosa and short-rib thoracic dysplasia 9 with or without polydactyly. Is an ortholog of human IFT140 (intraflagellar transport 140).