RNF32-AS1

Homo sapiens

ASSOCIATED WITH Autism; autistic disorder; Patterson Stevenson Syndrome

LINC00244

Homo sapiens

ASSOCIATED WITH Autism; autistic disorder; Patterson Stevenson Syndrome; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; nickel sulfate

scl-21

Caenorhabditis elegans

Predicted to be located in extracellular space. Is an ortholog of human CLEC18A (C-type lectin domain family 18 member A); CLEC18B (C-type lectin domain family 18 member B); and CLEC18C (C-type lectin domain family 18 member C).

C35D10.17

Caenorhabditis elegans

Predicted to be located in mitochondrion. Is an ortholog of human CMC2 (C-X9-C motif containing 2).

Dusp18

Homo sapiens

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]

Dusp14

Homo sapiens

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]

R02F11.12

Caenorhabditis elegans

Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin-like; and C-type lectin fold.

npr-20

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and lung disease (multiple). Is an ortholog of several human genes including CCR1 (C-C motif chemokine receptor 1); CCR3 (C-C motif chemokine receptor 3); and CXCR5 (C-X-C motif chemokine receptor 5).

clec-122

Caenorhabditis elegans

Is affected by several genes including pmk-1; glh-4; and glh-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin-like/link domain superfamily; T-complex protein 10, C-terminal domain superfamily; C-type lectin-like; and C-type lectin fold.

Dusp19

Homo sapiens

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]