- Poxn [Search on AGR]
Drosophila melanogaster Pox neuro (Poxn) encodes a transcriptional factor that specifies the differences between mono-innervated external sensory (m-es) organs and poly-innervated external sensory (p-es) organs. Poxn expression in the external sensory organ precursor determines the fate to form larval p-es organs and adult chemosensory bristles.
- DcpS [Search on AGR]
Mus musculus PHENOTYPE: A mutant mouse line was generated from gene-trapped ES cells, but no phenotypic information is available. [provided by MGI curators]
- Nanog [Search on AGR]
Homo sapiens The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
- Nhej1 [Search on AGR]
Mus musculus PHENOTYPE: Homozygous null ES cells are sensitive to ionizing radiation and have defects in DNA repair. Lymphocyte numbers are modestly decreased in null homozygous mice. [provided by MGI curators]
- COX7B [Search on AGR]
Mus musculus PHENOTYPE: Male chimeras hemizygous for a gene trapped allele appear normal at E6.5. However, no embryos fully derived from mutant ES cells can be generated. [provided by MGI curators]
- Nap1l2 [Search on AGR]
Mus musculus PHENOTYPE: Chimeric embryos with high contribution from heterozygous or homozygous null mutant ES cells exhibit severely abnormal neural tube development and die by embryonic day 14 (E14). [provided by MGI curators]
- Thap11 [Search on AGR]
Mus musculus PHENOTYPE: Homozygous inactivation of this gene leads to peri-implantation lethality and defects in the inner cell mass. Homozygous null ES cells are not viable. [provided by MGI curators]
- Hsd17b12 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a gene trap allele exhibit die around E8.5 with abnormal embryonic and extraembryonic tissue development. ES cells heterozygous for this allele exhibit reduced arachidonic acid levels. [provided by MGI curators]
- Atp6ap1 [Search on AGR]
Mus musculus PHENOTYPE: A targeted mutation in this X-linked gene was made in male ES cells, but no viable chimeric mice were produced, suggesting a requirement for this gene in prenatal development. [provided by MGI curators]
- TDP2 [Search on AGR]
Mus musculus PHENOTYPE: Homozygous mutant mice carrying a gene trap insertion into intron 5 but subsequently shown to harbor a partial duplication of the wild-type allele at the ES cell level are born with a normal Mendelian distribution. [provided by MGI curators]