scl-21

Caenorhabditis elegans

Predicted to be located in extracellular space. Is an ortholog of human CLEC18A (C-type lectin domain family 18 member A); CLEC18B (C-type lectin domain family 18 member B); and CLEC18C (C-type lectin domain family 18 member C).

C35D10.17

Caenorhabditis elegans

Predicted to be located in mitochondrion. Is an ortholog of human CMC2 (C-X9-C motif containing 2).

R02F11.12

Caenorhabditis elegans

Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin-like; and C-type lectin fold.

npr-20

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and lung disease (multiple). Is an ortholog of several human genes including CCR1 (C-C motif chemokine receptor 1); CCR3 (C-C motif chemokine receptor 3); and CXCR5 (C-X-C motif chemokine receptor 5).

clec-122

Caenorhabditis elegans

Is affected by several genes including pmk-1; glh-4; and glh-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin-like/link domain superfamily; T-complex protein 10, C-terminal domain superfamily; C-type lectin-like; and C-type lectin fold.

clec-15

Caenorhabditis elegans

Is affected by several genes including cyd-1; etr-1; and rsr-2 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including Oligosaccharides; cadmium; and quercetin based on microarray studies. Is predicted to encode a protein with the following domains: CUB domain; Snake venom C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; Spermadhesin, CUB domain superfamily; C-type lectin-like; and C-type lectin fold.

clec-18

Caenorhabditis elegans

Is affected by several genes including hpl-2; glp-1; and mir-34 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including resveratrol; Atrazine; and Chlorpyrifos based on microarray studies. Is predicted to encode a protein with the following domains: CUB domain; Snake venom C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; Spermadhesin, CUB domain superfamily; C-type lectin-like; and C-type lectin fold.

clec-100

Caenorhabditis elegans

Is affected by several genes including qui-1; rsr-2; and hrde-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin-like; and C-type lectin fold.

clec-132

Caenorhabditis elegans

Enriched in NSM based on tiling array studies. Is affected by lpd-3 based on RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin-like/link domain superfamily; C-type lectin-like; and C-type lectin fold.

pll-1

Caenorhabditis elegans

Predicted to enable phosphatidylinositol phospholipase C activity. Predicted to be involved in gamma-aminobutyric acid signaling pathway and regulation of GABAergic synaptic transmission. Expressed in AIYL and AIYR. Is an ortholog of human PLCL1 (phospholipase C like 1 (inactive)) and PLCL2 (phospholipase C like 2).