ddo-2

Caenorhabditis elegans

Enables D-aspartate oxidase activity and D-glutamate oxidase activity. Involved in aspartate catabolic process. Predicted to be located in peroxisomal matrix. Expressed in body wall musculature; intestinal cell; and pharyngeal muscle cell.

daao-1

Caenorhabditis elegans

Enables D-amino-acid oxidase activity. Predicted to be involved in D-amino acid catabolic process and digestion. Predicted to be located in cytoplasm. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human DDO (D-aspartate oxidase).

ddo-1

Caenorhabditis elegans

Enables D-aspartate oxidase activity; D-glutamate oxidase activity; and FAD binding activity. Predicted to be involved in D-amino acid catabolic process. Predicted to be located in peroxisomal matrix. Expressed in hypodermis and intestinal cell. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human DAO (D-amino acid oxidase).

F32D8.12

Caenorhabditis elegans

Predicted to enable D-lactate dehydrogenase (cytochrome) activity; D-lactate dehydrogenase activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in lactate catabolic process. Predicted to be located in mitochondrion. Is an ortholog of human LDHD (lactate dehydrogenase D).

sos-1

Caenorhabditis elegans

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; female gamete generation; and positive regulation of vulval development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 4; Noonan syndrome 9; and reproductive organ cancer (multiple). Is an ortholog of human SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1).

gsp-1

Caenorhabditis elegans

Predicted to enable protein serine/threonine phosphatase activity. Involved in negative regulation of protein phosphorylation and positive regulation of gene expression. Predicted to be located in cytoplasm and nucleus. Expressed in oocyte. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 2. Is an ortholog of human PPP1CB (protein phosphatase 1 catalytic subunit beta).

F09G2.8

Caenorhabditis elegans

Predicted to enable phospholipase D activity. Predicted to be involved in lipid catabolic process. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 46. Is an ortholog of human PLD3 (phospholipase D family member 3) and PLD4 (phospholipase D family member 4).

R119.5

Caenorhabditis elegans

Predicted to enable protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. Predicted to be involved in protein modification process. Predicted to be located in cytoplasm. Is an ortholog of human PCMTD1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1) and PCMTD2 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2).

ras-2

Caenorhabditis elegans

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in signal transduction. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 11. Is an ortholog of human MRAS (muscle RAS oncogene homolog).

mcp-1

Caenorhabditis elegans

Enables GDP-D-glucose phosphorylase activity. Involved in glucose metabolic process. Located in cytoplasm. Expressed in anterior hypodermis; nervous system; reproductive system; and spermatheca. Is an ortholog of human GDPGP1 (GDP-D-glucose phosphorylase 1).