mboa-3

Caenorhabditis elegans

Predicted to enable acyltransferase activity. Predicted to be involved in lipid modification. Predicted to be located in membrane. Is an ortholog of human MBOAT1 (membrane bound O-acyltransferase domain containing 1) and MBOAT2 (membrane bound O-acyltransferase domain containing 2).

mboa-4

Caenorhabditis elegans

Predicted to enable acyltransferase activity. Predicted to be involved in lipid modification. Predicted to be located in membrane. Is an ortholog of human MBOAT1 (membrane bound O-acyltransferase domain containing 1) and MBOAT2 (membrane bound O-acyltransferase domain containing 2).

pssy-1

Caenorhabditis elegans

Predicted to enable L-serine-phosphatidylethanolamine phosphatidyltransferase activity. Predicted to be involved in phosphatidylserine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Lenz-Majewski hyperostotic dwarfism. Is an ortholog of human PTDSS1 (phosphatidylserine synthase 1).

Cpsf1

Homo sapiens

Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008]

ps

Drosophila melanogaster

pasilla (ps) encodes a nuclear RNA binding protein implicated in splicing. It is expressed at high levels in the embryonic salivary gland and other tissues. Loss of function results in a significant reduction in secretory volume and secretory vesicles in the salivary gland and irregular gland morphology.

mboa-6

Caenorhabditis elegans

Predicted to enable 1-acylglycerophosphocholine O-acyltransferase activity and lysophospholipid acyltransferase activity. Involved in glycerophospholipid biosynthetic process; positive regulation of growth rate; and post-embryonic development. Predicted to be located in endoplasmic reticulum and membrane. Expressed in pharyngeal muscle cell and tail. Is an ortholog of human LPCAT3 (lysophosphatidylcholine acyltransferase 3).

Ulk2

Homo sapiens

This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008]