Npr2

Rattus norvegicus

Enables peptide hormone binding activity. Involved in cGMP-mediated signaling; positive regulation of signal transduction; and wound healing. Predicted to be located in synapse. Predicted to be active in several cellular components, including cilium; neuron projection; and nucleus. Human ortholog(s) of this gene implicated in Miura type epiphyseal chondrodysplasia; acromesomelic dysplasia, Maroteaux type; and essential hypertension. Orthologous to human NPR2 (natriuretic peptide receptor 2); PARTICIPATES IN C-type natriuretic peptide signaling pathway; purine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.