Y53F4B.12

Caenorhabditis elegans

Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to be located in plasma membrane.

acox-1.5

Caenorhabditis elegans

Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in pheromone biosynthetic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Mitchell syndrome and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

F08F3.4

Caenorhabditis elegans

Predicted to enable L-threonine 3-dehydrogenase activity. Involved in innate immune response. Is an ortholog of human TDH (L-threonine dehydrogenase (pseudogene)).

acox-1.3

Caenorhabditis elegans

Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in ascaroside biosynthetic process and pheromone biosynthetic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Mitchell syndrome; congenital bile acid synthesis defect 6; and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

acox-1.2

Caenorhabditis elegans

Enables ATP binding activity and acyl-CoA oxidase activity. Involved in ascaroside biosynthetic process and fatty acid beta-oxidation using acyl-CoA oxidase. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Mitchell syndrome; congenital bile acid synthesis defect 6; and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

C15B12.1

Caenorhabditis elegans

Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase).

C15B12.8

Caenorhabditis elegans

Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase).

acox-1.4

Caenorhabditis elegans

Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in ascaroside biosynthetic process and pheromone biosynthetic process. Predicted to be located in peroxisome. Expressed in intestine. Human ortholog(s) of this gene implicated in Mitchell syndrome; congenital bile acid synthesis defect 6; and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

acox-1.6

Caenorhabditis elegans

Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA oxidase and lipid homeostasis. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Mitchell syndrome and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

irld-26

Caenorhabditis elegans

Is affected by several genes including drh-3; sir-2.1; and lin-14 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L domain; Receptor L-domain; SPS2 domain-containing protein; and Receptor L-domain superfamily.