acox-1.5

Caenorhabditis elegans

Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in pheromone biosynthetic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Mitchell syndrome and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

acox-1.3

Caenorhabditis elegans

Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in ascaroside biosynthetic process and pheromone biosynthetic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Mitchell syndrome; congenital bile acid synthesis defect 6; and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

acox-1.2

Caenorhabditis elegans

Enables ATP binding activity and acyl-CoA oxidase activity. Involved in ascaroside biosynthetic process and fatty acid beta-oxidation using acyl-CoA oxidase. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Mitchell syndrome; congenital bile acid synthesis defect 6; and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

acox-1.4

Caenorhabditis elegans

Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in ascaroside biosynthetic process and pheromone biosynthetic process. Predicted to be located in peroxisome. Expressed in intestine. Human ortholog(s) of this gene implicated in Mitchell syndrome; congenital bile acid synthesis defect 6; and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

acox-1.6

Caenorhabditis elegans

Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA oxidase and lipid homeostasis. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Mitchell syndrome and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

acox-1.1

Caenorhabditis elegans

Enables ATP binding activity and acyl-CoA oxidase activity. Involved in ascaroside biosynthetic process; fatty acid beta-oxidation using acyl-CoA oxidase; and pheromone biosynthetic process. Located in peroxisomal matrix. Expressed in hypodermis; intestinal cell; and intestine. Human ortholog(s) of this gene implicated in Mitchell syndrome; congenital bile acid synthesis defect 6; and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1).

asp-3

Caenorhabditis elegans

Predicted to enable aspartic-type endopeptidase activity. Involved in programmed necrotic cell death. Located in lysosome. Expressed in intestine and uterus. Is an ortholog of human NAPSA (napsin A aspartic peptidase).

unc-58

Caenorhabditis elegans

Enables outward rectifier potassium channel activity. Involved in several processes, including muscle contraction; parturition; and regulation of muscle contraction. Predicted to be located in plasma membrane. Expressed in interneuron and motor neurons. Is an ortholog of human KCNK17 (potassium two pore domain channel subfamily K member 17) and KCNK5 (potassium two pore domain channel subfamily K member 5).

asp-4

Caenorhabditis elegans

Predicted to enable aspartic-type endopeptidase activity. Involved in programmed necrotic cell death. Located in lysosome. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; and neuronal ceroid lipofuscinosis 10. Is an ortholog of human CTSD (cathepsin D).

gbas-1

Caenorhabditis elegans

Enables G-protein alpha-subunit binding activity and guanyl-nucleotide exchange factor activity. Involved in small GTPase-mediated signal transduction. Expressed in several structures, including GLR; coelomocyte; distal tip cell; intestine; and neurons.