- Cpa3 [Search on AGR]
Mus musculus PHENOTYPE: Homozygous null mice have immature peritoneal mast cells but normal mast cell functions. [provided by MGI curators]
- Milr1 [Search on AGR]
Rattus norvegicus Predicted to be involved in mast cell degranulation and negative regulation of mast cell activation. Predicted to be located in plasma membrane. Orthologous to human MILR1 (mast cell immunoglobulin like receptor 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 4,4'-diaminodiphenylmethane.
- Ormdl1 [Search on AGR]
Mus musculus PHENOTYPE: Homozygous null mice show normal intracellular calcium levels and granulation in mast cells upon activation and normal mast cell ceramide levels. [provided by MGI curators]
- Prss57 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a null allele display reduced levels of histamine and serotonin in mast cells resulting in defects in mast cell function. [provided by MGI curators]
- Srgn [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for disruptions in this gene lack peritoneal mast cells. [provided by MGI curators]
- Mitf [Search on AGR]
Mus musculus PHENOTYPE: Mutations at this locus affect development of melanocytes, mast cells, osteoclasts and pigmented epithelium. Mutants variably display lack of pigment in coat and eye, microphthalmia, hearing loss, bone resorption anomalies, mast cell deficiency and lethality. [provided by MGI curators]
- Coro1b [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal mast cell degranulation. [provided by MGI curators]
- Lat2 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a null allele have abnormal mast cell physiology and increased anti-nuclear antigen antibody level. Mice homozygous for another null allele show abnormal mast cell physiology, hyperactivated T cells, higher cytokine production, spleenhyperplasia and increased autoantibody level. [provided by MGI curators]
- Rgs13 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a null allele exhibit increased mast cell degranulation and increased anaphylaxis. [provided by MGI curators]
- Ms4a2 [Search on AGR]
Mus musculus PHENOTYPE: Homozygous null mice display decreased susceptibility to passive cutaneous anaphylaxis and abnormal mast cell physiology. [provided by MGI curators]