col-179

Caenorhabditis elegans

Predicted to be a structural constituent of cuticle. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in Stickler syndrome; multiple epiphyseal dysplasia 2; and pulmonary tuberculosis. Is an ortholog of human COL9A2 (collagen type IX alpha 2 chain) and MARCO (macrophage receptor with collagenous structure).

col-181

Caenorhabditis elegans

Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Is an ortholog of human COL5A3 (collagen type V alpha 3 chain) and MARCO (macrophage receptor with collagenous structure).

Marco

Rattus norvegicus

Enables G protein-coupled receptor binding activity; amyloid-beta binding activity; and cargo receptor activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; endocytosis; and positive regulation of ERK1 and ERK2 cascade. Located in cytoplasm and plasma membrane. Used to study silicosis. Biomarker of meningococcal meningitis. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to human MARCO (macrophage receptor with collagenous structure); PARTICIPATES IN phagocytosis pathway; INTERACTS WITH 17beta-estradiol; acetamide; aflatoxin B1.