Y53F4B.12

Caenorhabditis elegans

Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to be located in plasma membrane.

acs-13

Caenorhabditis elegans

Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Expressed in head. Human ortholog(s) of this gene implicated in acute myeloid leukemia; congenital diarrhea; and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1); ACSL5 (acyl-CoA synthetase long chain family member 5); and ACSL6 (acyl-CoA synthetase long chain family member 6).

acs-18

Caenorhabditis elegans

Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1) and ACSL6 (acyl-CoA synthetase long chain family member 6).

acs-15

Caenorhabditis elegans

Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1) and ACSL6 (acyl-CoA synthetase long chain family member 6).

acs-17

Caenorhabditis elegans

Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA metabolic process; and neuron differentiation. Predicted to be located in endoplasmic reticulum; lipid droplet; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including lung cancer; non-syndromic X-linked intellectual disability 63; and prostate cancer. Is an ortholog of human ACSL3 (acyl-CoA synthetase long chain family member 3) and ACSL4 (acyl-CoA synthetase long chain family member 4).

acs-4

Caenorhabditis elegans

Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA metabolic process; and neuron differentiation. Located in lipid droplet. Expressed in gonadal sheath cell; hypodermis; intestine; pharynx; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including lung cancer; non-syndromic X-linked intellectual disability 63; and prostate cancer. Is an ortholog of human ACSL3 (acyl-CoA synthetase long chain family member 3) and ACSL4 (acyl-CoA synthetase long chain family member 4).

F08F3.4

Caenorhabditis elegans

Predicted to enable L-threonine 3-dehydrogenase activity. Involved in innate immune response. Is an ortholog of human TDH (L-threonine dehydrogenase (pseudogene)).

C15B12.1

Caenorhabditis elegans

Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase).

C15B12.8

Caenorhabditis elegans

Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase).

acs-5

Caenorhabditis elegans

Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Expressed in hypodermis. Human ortholog(s) of this gene implicated in congenital diarrhea. Is an ortholog of human ACSL5 (acyl-CoA synthetase long chain family member 5).