- Jevr [Search on AGR]
Mus musculus PHENOTYPE: Strains respond differently to Japanese encephalitis virus (JEV) infection. For intraperitoneal inoculation, C3H/He mice show high infection and mortality rates; C57BL/6, RR, NC and KK mice show high infection and low mortality. AA, BALB/c and ddY mice show low infection and no mortality. [provided by MGI curators]
- Cul4a [Search on AGR]
Homo sapiens CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM, Oct 2009]
- ckk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables calmodulin binding activity and calmodulin-dependent protein kinase activity. Predicted to be involved in CAMKK-AMPK signaling cascade. Located in cytoplasm and nucleus. Expressed in head neurons; tail neurons; and vulval muscle. Human ortholog(s) of this gene implicated in high grade glioma. Is an ortholog of human CAMKK1 (calcium/calmodulin dependent protein kinase kinase 1).
- Styk1 [Search on AGR]
Homo sapiens Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008]
- Cytl1 [Search on AGR]
Homo sapiens C17 is a cytokine-like protein specifically expressed in bone marrow and cord blood mononuclear cells that bear the CD34 (MIM 142230) surface marker (Liu et al., 2000 [PubMed 10857752]).[supplied by OMIM, Mar 2008]
- Atf7ip [Search on AGR]
Homo sapiens ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010]
- Ppp1r14d [Search on AGR]
Homo sapiens Protein phosphatase-1 (PP1; see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation. PPP1R14D is a PP1 inhibitor that itself is regulated by phosphorylation (Liu et al., 2004 [PubMed 12974676]).[supplied by OMIM, Feb 2010]
- Hpd [Search on AGR]
Mus musculus PHENOTYPE: CBA, C3H, DBA/2, SM and AKR have the F.1 form of this soluble liver antigen; A/J, A2G, BALB/c and C57BL/10 the F.2 form. F.2 antigen induces precipitating antibodies in F.1 but not F.2 strains and vice versa. F antigen immune response requires H2 Kk or Ak alleles. [provided by MGI curators]
- Tpe1 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls electrophoretic variation of a protein in tears. A co-dominant fast band is seen in C3H/He, CBA/N, IC/Le, KK, SWM/MS, WB/Re and WC/Re; a co-dominant slow band in DBA/1, DBA/2, C57L, NZB, NZW and SM; and a recessive null allele (no band) in BALB/c, A/He, AKR, CL/Fr, DDD and NC. [provided by MGI curators]
- Ppp1r14c [Search on AGR]
Homo sapiens The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied by OMIM, Feb 2010]