lin-53

Caenorhabditis elegans

Enables histone deacetylase binding activity. Involved in several processes, including cell fate specification; embryonic digestive tract morphogenesis; and nematode male tail tip morphogenesis. Acts upstream of or within mitochondrial unfolded protein response. Located in nucleus. Part of DRM complex and NuRD complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human RBBP4 (RB binding protein 4, chromatin remodeling factor) and RBBP7 (RB binding protein 7, chromatin remodeling factor).

lin-25

Caenorhabditis elegans

Involved in defense response to Gram-positive bacterium and vulval development. Acts upstream of or within with a positive effect on cell fate specification. Located in cytoplasm and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; hermaphrodite distal tip cell; and vulval cell.

ZK673.4

Caenorhabditis elegans

Predicted to enable metal ion binding activity.

lin-4

Caenorhabditis elegans

Enables mRNA 3'-UTR binding activity. Involved in several processes, including egg-laying behavior; mating; and negative regulation of gene expression. Expressed in several structures, including P5.p hermaphrodite; P7.p hermaphrodite; gonad; neurons; and ventral nerve cord.

lin-15A

Caenorhabditis elegans

Involved in several processes, including negative regulation of vulval development; protein stabilization; and vulval development. Located in nucleus. Expressed in gonad.

ets-6

Caenorhabditis elegans

Predicted to be involved in negative regulation of vulval development.

F19F10.11

Caenorhabditis elegans

Predicted to be involved in negative regulation of vulval development.

Y32B12B.4

Caenorhabditis elegans

Predicted to be involved in negative regulation of vulval development.

lin-31

Caenorhabditis elegans

Enables sequence-specific DNA binding activity. Involved in vulval development. Located in nucleus. Expressed in several structures, including P11.p; P9.p; gonad; nerve ring; and vulval precursor cell. Is an ortholog of human FOXB2 (forkhead box B2).

lin-18

Caenorhabditis elegans

Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. Located in cytoplasm; nucleus; and plasma membrane. Expressed in body wall musculature; neurons; vulva; and vulval precursor cell. Is an ortholog of human RYK (receptor like tyrosine kinase).