srj-22

Caenorhabditis elegans

Predicted to be located in membrane. Expressed in CP neuron and odorsensory neurons.

srj-21

Caenorhabditis elegans

Predicted to be located in membrane. Expressed in CP neuron and odorsensory neurons.

C24A3.9

Caenorhabditis elegans

Enriched in CP neuron and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by rsr-2; clk-1; and lsm-1 based on tiling array; microarray; and RNA-seq studies.

Y41E3.461

Caenorhabditis elegans

Enriched in CP neuron based on single-cell RNA-seq studies. Is affected by adr-1; unc-30; and ogt-1 based on RNA-seq studies. Is affected by Doxycycline and paraquat based on RNA-seq studies.

W02H3.2

Caenorhabditis elegans

Enriched in AIAL; AIYL; AIYR; CP neuron; and RID based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including etr-1; unc-39; and smg-2 based on microarray and RNA-seq studies.

M02E1.4

Caenorhabditis elegans

Enriched in CP neuron and nerve ring neurons based on single-cell RNA-seq studies. Is affected by several genes including unc-25; inx-14; and tmc-1 based on RNA-seq studies. Is affected by leptomycin B based on RNA-seq studies.

M02F4.2

Caenorhabditis elegans

Enriched in CP neuron and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including cyc-1; rsr-2; and dpy-21 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq and microarray studies.

BLM10

Saccharomyces cerevisiae

Proteasome activator; binds the core proteasome (CP) and stimulates proteasome-mediated protein degradation by inducing gate opening; required for sequestering CP into proteasome storage granule (PSG) during quiescent phase and for nuclear import of CP in proliferating cells; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200

ZK1251.5

Caenorhabditis elegans

Enriched in AVK; AVKL; CP neuron; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cyc-1; nuo-6; and atfs-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Ethanol; manganese chloride; and Psoralens based on RNA-seq and microarray studies.

chk-2

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mitotic DNA damage checkpoint signaling. Predicted to be located in cytoplasm and nucleus. Expressed in germline blastomere. Human ortholog(s) of this gene implicated in several diseases, including Li-Fraumeni syndrome 2; breast cancer (multiple); and germ cell cancer (multiple). Is an ortholog of human CHEK2 (checkpoint kinase 2).