- rpsa-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal small subunit assembly. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic small ribosomal subunit. Expressed in tail. Is an ortholog of human RPSA (ribosomal protein SA).
- PGRP-SA [Search on AGR]
Drosophila melanogaster Peptidoglycan recognition protein SA (PGRP-SA) encodes a secreted protein that mediates Toll pathway activation during bacterial infection. It binds to peptidoglycans and, together with the product of GNBP1, activates the serine protease encoded by modSP.
- Fut7 [Search on AGR]
Homo sapiens The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X antigens. The encoded protein can direct the synthesis of the E-selectin-binding sialyl-Lewis X moiety. [provided by RefSeq, Jul 2008]
- fut-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity and glycoprotein 3-alpha-L-fucosyltransferase activity. Involved in carbohydrate biosynthetic process and fucosylation. Predicted to be located in Golgi membrane. Expressed in chemosensory neurons; pharyngeal-intestinal valve; rectal valve cell; and retrovesicular ganglion. Is an ortholog of human FUT3 (fucosyltransferase 3 (Lewis blood group)); FUT5 (fucosyltransferase 5); and FUT6 (fucosyltransferase 6).
- fah-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable fumarylacetoacetase activity. Predicted to be involved in L-phenylalanine catabolic process; homogentisate catabolic process; and tyrosine catabolic process. Expressed in hypodermis. Used to study tyrosinemia type I. Human ortholog(s) of this gene implicated in tyrosinemia type I. Is an ortholog of human FAH (fumarylacetoacetate hydrolase).
- sa [Search on AGR]
Drosophila melanogaster spermatocyte arrest (sa) encodes a testis binding protein associated factor involved in control of the male meiotic cycle, gene expression regulation, and spermatid differentiation.
- FUT3 [Search on AGR]
Homo sapiens The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Differences in the expression of this gene are associated with host susceptibility to viral infection. [provided by RefSeq, Aug 2020]
- cpi-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cysteine-type endopeptidase inhibitor activity. Involved in positive regulation of vitellogenesis; regulation of oocyte development; and regulation of protein processing. Located in extracellular space and yolk granule. Expressed in hypodermis; pharyngeal gland cell; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of several human genes including CST1 (cystatin SN); CST2 (cystatin SA); and CST3 (cystatin C).
- Fut4 [Search on AGR]
Homo sapiens The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009]
- Chst2 [Search on AGR]
Homo sapiens This locus encodes a sulfotransferase protein. The encoded enzyme catalyzes the sulfation of a nonreducing N-acetylglucosamine residue, and may play a role in biosynthesis of 6-sulfosialyl Lewis X antigen. [provided by RefSeq, Aug 2011]