- Wdr82 [Search on AGR]
Homo sapiens TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010]
- Fili [Search on AGR]
Drosophila melanogaster Fish-lips (Fili) encodes a leucine-rich repeat family transmembrane protein. It regulates autonomous and nonautonomous apoptosis caused by the dioxin receptor homolog encoded by ss.
- LHP1 [Search on AGR]
Saccharomyces cerevisiae RNA binding protein required for maturation of tRNA and U6 snRNA; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen
- Gipc1 [Search on AGR]
Homo sapiens GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009]
- chhy-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables hexosaminidase activity. Involved in chondroitin sulfate catabolic process. Expressed in PLML; PLMR; head; intestinal cell; and vulva. Human ortholog(s) of this gene implicated in mucopolysaccharidosis IX. Is an ortholog of human HYAL2 (hyaluronidase 2).
- Setd1b [Search on AGR]
Homo sapiens SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Mar 2008]
- St6galnac3 [Search on AGR]
Homo sapiens ST6GALNAC3 belongs to a family of sialyltransferases that transfer sialic acids from CMP-sialic acid to terminal positions of carbohydrate groups in glycoproteins and glycolipids (Lee et al., 1999 [PubMed 10207017]).[supplied by OMIM, Mar 2008]
- ss [Search on AGR]
Drosophila melanogaster spineless (ss) encodes a protein that plays a key role in defining the distal regions of the antenna and the leg. Its stochastic expression in R7 photoreceptors also controls the expression of color Rhodopsins (the product of Rh4 vs. the product of Rh3) in the two subsets of ommatidia.
- Prmt8 [Search on AGR]
Homo sapiens Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]
- Ssna1 [Search on AGR]
Rattus norvegicus Predicted to enable identical protein binding activity and microtubule binding activity. Predicted to be involved in axonogenesis; cell division; and microtubule nucleation. Predicted to act upstream of or within intraciliary transport and receptor clustering. Predicted to be located in several cellular components, including axon; cytoskeleton; and midbody. Predicted to be active in centrosome and ciliary basal body. Orthologous to human SSNA1 (SS nuclear autoantigen 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 4,4'-sulfonyldiphenol.