- SK [Search on AGR]
Drosophila melanogaster small conductance calcium-activated potassium channel (SK) encodes a potassium channel subunit. Four SK subunits together form a voltage-independent potassium channel, which is activated by intracellular calcium levels and is required for normal photoreceptor light response. Contrary to its mammalian counterpart, Drosophila SK channel is not sensitive to apamin, at least not in photoreceptors.
- Wdr82 [Search on AGR]
Homo sapiens TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010]
- Gipc1 [Search on AGR]
Homo sapiens GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009]
- Setd1b [Search on AGR]
Homo sapiens SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Mar 2008]
- St6galnac3 [Search on AGR]
Homo sapiens ST6GALNAC3 belongs to a family of sialyltransferases that transfer sialic acids from CMP-sialic acid to terminal positions of carbohydrate groups in glycoproteins and glycolipids (Lee et al., 1999 [PubMed 10207017]).[supplied by OMIM, Mar 2008]
- Prt4 [Search on AGR]
Mus musculus PHENOTYPE: Prt4 and Prt5 loci control electrophoretic mobility of two esteroproteases inducible by testosterone in submandibular glands. Prt4 alleles are: a allele in DBA/2, M.m. molossinus and M.m. castaneus; b allele in C57BL/10, A/J, NMRI/F and SK/Cam. Heterozygotes have all parental bands. [provided by MGI curators]
- Es9 [Search on AGR]
Mus musculus PHENOTYPE: Five electrophoretically distinguishable alleles are: the a allele in strains NMRI, C3H and C57BL/Gr; the b allele in SK/Cam; the c allele in M. m. molossinus; the d allele in some Peru-Coppock mice; the e allele in Peru/1Fr. Heterozygotes have intermediate patterns. [provided by MGI curators]
- Prmt8 [Search on AGR]
Homo sapiens Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]
- Es23 [Search on AGR]
Mus musculus PHENOTYPE: This carboxylesterase is active with substrates 5-bromoindoxyl acetate and alpha-naphthyl butyrate. Five electrophoretic alleles are known: a in M.m. molossinus; b in M.m. castaneus; c in C57BL/10 and most inbreds; d (null) in SK/Cam; e in M. spretus. The b allele also determines expression in lung. [provided by MGI curators]
- Asmt [Search on AGR]
Mus musculus PHENOTYPE: Pineal melatonin synthesis requires enzymes encoded by Asmt and Aanat. C57BL/6, BALB/c, AKR/J, NZB/Bl, IS/Cam, and CAST/Ei carry the a allele of Asmt and lack melatonin. SK/Cam, SF/Cam, PERU, and FDS carry the b allele and have normal melatonin levels. [provided by MGI curators]