- Osr2 [Search on AGR]
Homo sapiens OSR2 is a mammalian homolog of the Drosophila odd-skipped family of transcription factors (Lan et al., 2004 [PubMed 15175245]).[supplied by OMIM, Mar 2008]
- Rit2 [Search on AGR]
Homo sapiens RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied by OMIM, Mar 2008]
- hts [Search on AGR]
Drosophila melanogaster hu li tai shao (hts) encodes an adducin homolog that is associated with the plasma membrane cytoskeleton, fusome and oocyte ring canals. It has essential functions in muscle, nerve and other tissues, and is required for fertility in males and females.
- hmt-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cadmium ion transmembrane transporter activity. Involved in cadmium ion transmembrane transport; cellular detoxification of cadmium ion; and detoxification of copper ion. Located in endosome and vacuolar membrane. Expressed in coelomocyte; head neurons; intestinal cell; and tail neurons. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Is an ortholog of human ABCB6 (ATP binding cassette subfamily B member 6 (LAN blood group)).
- Abcb6 [Search on AGR]
Rattus norvegicus Predicted to enable several functions, including ABC-type heme transporter activity; ATP binding activity; and ATP hydrolysis activity. Involved in intracellular copper ion homeostasis. Located in early endosome membrane; endolysosome membrane; and late endosome membrane. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Orthologous to human ABCB6 (ATP binding cassette subfamily B member 6 (LAN blood group)); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; allethrin.
- Abcb6 [Search on AGR]
Homo sapiens This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the heavy metal importer subfamily and plays a role in porphyrin transport. This gene is the molecular basis of the Langereis (Lan) blood group antigen and mutations in this gene underlie familial pseudohyperkalemia and dyschromatosis universalis hereditaria. [provided by RefSeq, Mar 2017]