Involved in positive regulation of locomotion. Predicted to be located in basement membrane. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; lung small cell carcinoma; and lung squamous cell carcinoma. Is an ortholog of human LAMC1 (laminin subunit gamma 1).
Involved in pharynx development and positive regulation of locomotion. Located in basement membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including Pierson syndrome; amelogenesis imperfecta type 1A; and lung carcinoma (multiple). Is an ortholog of human LAMB1 (laminin subunit beta 1) and LAMB2 (laminin subunit beta 2).
Predicted to be involved in animal organ morphogenesis; axonogenesis; and tissue development. Located in basement membrane. Expressed in several structures, including excretory canal; pharyngeal-intestinal valve; pharynx; somatic nervous system; and spermatheca. Used to study muscular dystrophy. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy; congenital merosin-deficient muscular dystrophy 1A; and myopia. Is an ortholog of human LAMA1 (laminin subunit alpha 1) and LAMA2 (laminin subunit alpha 2).
Predicted to enable translation release factor activity. Predicted to be involved in translational termination. Is an ortholog of C. elegans lam-1. In C. elegans, lam-1 is involved in pharynx development and positive regulation of locomotion.