High-affinity copper transporter of the plasma membrane; acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae
PHENOTYPE: In a controlled microbial environment ("clean") laboratory, mice homozygous for an inactivating mutation of this gene are viable and fertile and exhibit no apparent abonormal phenotype. [provided by MGI curators]
PHENOTYPE: Reciprocal alloimmunization between a Mus musculus molossinus-derived strain and a standard laboratory strain of mice identified two serum protein antigens, encoded by Alph1 and Alph2. [provided by MGI curators]
PHENOTYPE: Reciprocal alloimmunization between a Mus musculus molossinus-derived strain and a standard laboratory strain of mice identified two serum protein antigens, encoded by Alph1 and Alph2. [provided by MGI curators]
PHENOTYPE: MHC recombinants between wild-derived H2<wm7> and laboratory chromosomes show high rates of mutation that may be unlinked to MHC, but appear to be induced by the intra-MHC recombination. [provided by MGI curators]
PHENOTYPE: At 8 weeks of age, consuming standard laboratory chow containing 6% fat, mice with a mutation of this gene have elevated plasma high density lipoprotein (HDL) cholesterol after a 4 hour fast. [provided by MGI curators]
PHENOTYPE: By 8 weeks of age, consuming standard laboratory chow containing 6% fat, mice with a mutation of this gene have significantly elevated plasma high density lipoprotein (HDL) cholesterol after a 4 hour fast. [provided by MGI curators]
invected (inv) encodes a homeodomain transcription factor that is closely related to, co-expressed with, and functionally redundant with the product of en. Although dispensable in the laboratory, the product of inv is a transcriptional repressor important for segmentation in the embryo and formation of the posterior compartment in imaginal discs.
PHENOTYPE: Mice homozygous for a targeted null allele have abnormal incisor and molar root development, show reduced alveolar bone formation, and exhibit impaired feeding leading to severe runting and premature death when reared on standard laboratory chow. [provided by MGI curators]
PHENOTYPE: Es30 is an isozymic form of carboxylesterase. In liver it shows higher activity in males and is increased by testosterone. The n allele (null) is seen in Mus spretus-derived strains; the b allele is seen in BALB/c and other laboratory strains. [provided by MGI curators]