- mboa-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables O-acyltransferase activity. Involved in egg-laying behavior; nematode larval development; and phosphatidylinositol biosynthetic process. Located in intracellular membrane-bounded organelle. Expressed in several structures, including hermaphrodite distal tip cell; intestine; pharyngeal muscle cell; spermatheca; and vulva. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 57. Is an ortholog of human MBOAT7 (membrane bound O-acyltransferase domain containing 7).
- sn [Search on AGR]
Drosophila melanogaster singed (sn) encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The bundling activity of the product of sn is regulated by phosphorylation.
- Svs3a [Search on AGR]
Mus musculus PHENOTYPE: At this locus, the a allele determines a slow anodally migrating enzyme band and occurs in the B10.AKM/Sn strain; the b allele determines a faster band and occurs in AKR.M/Sn, C3H/He and C57BL/10Orl strains. Heterozygotes have the two parental bands. [provided by MGI curators]
- EPT1 [Search on AGR]
Saccharomyces cerevisiae sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability; EPT1 has a paralog, CPT1, that arose from the whole genome duplication
- cpi-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cysteine-type endopeptidase inhibitor activity. Predicted to be located in cytoplasm; extracellular space; and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of human CST1 (cystatin SN); CST3 (cystatin C); and CST4 (cystatin S).
- PFK26 [Search on AGR]
Saccharomyces cerevisiae 6-phosphofructo-2-kinase; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate; has negligible fructose-2,6-bisphosphatase activity; transcriptional regulation involves protein kinase A
- cpi-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cysteine-type endopeptidase inhibitor activity. Involved in positive regulation of vitellogenesis; regulation of oocyte development; and regulation of protein processing. Located in extracellular space and yolk granule. Expressed in hypodermis; pharyngeal gland cell; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of several human genes including CST1 (cystatin SN); CST2 (cystatin SA); and CST3 (cystatin C).
- PGS1 [Search on AGR]
Saccharomyces cerevisiae Phosphatidylglycerolphosphate synthase; catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis
- tsn-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity and nuclease activity. Involved in miRNA-mediated post-transcriptional gene silencing. Located in cytosol and nucleus. Part of RISC complex. Expressed in head and tail. Is an ortholog of human SND1 (staphylococcal nuclease and tudor domain containing 1).
- Cyssl1 [Search on AGR]
Rattus norvegicus Predicted to enable cysteine-type endopeptidase inhibitor activity. Predicted to be active in cytoplasm; extracellular space; and vesicle. Orthologous to human CST4 (cystatin S) and CST1 (cystatin SN).